There are a variety of resources available on the www that accelerate our ability to get the research and development done. Following is a list of our most favorite sites.
Projects we are involved in:
- NIH/NHLBI Program in Genomics Applications - Project 1, use of microarray on mouse models to identify human gene candidates for cardiac illness. We also handle all the informatics and data submission/archival.
- NIH/NCI Advanced Technology Program - This program funds our work on the DOC arrays and their application to cancer research.
- NIH/NCI SPORE Program - In collaboration with John Minna, we use gene expression microarrays to understand lung cancer. We also provide arrays and analysis service to all other NIH/NCI SPORE research groups.
- State of Texas ARP - Two of our projects are funded by the State of Texas, including the development of the hyperspectral imaging microscope and the work on Snide to identify SNPs.
- Beckman Coulter Collaboration - We are using the CEQ to sequence difficult regions and share our data with Beckman so that improvements can be made to base calling software. We are also developing codes for alignment and SNP calling.
- BioThreat Data Repository - We are currently working on a www-accessible data warehouse for those researching biological warfare pathogens.
Microarrays:
- UTSW's Microarray core - Skip Garner and Dr. Ron Butow co-direct this core for the university.
National Databases:
- American Type Culture Collection (ATCC) Collections of cell lines, clones, etc.
- Antibody Resource A catalog of antibody suppliers and other resources
- Atlas of Genetics and Cytogenetics Database of cancer types, diseases, and the genetic factors involved.
- BAC/PAC Resource Contains a genome-wide set of human BAC clones and BAC/PAC resources for several organisms
- BioMed Central (reviewed in Science 5-12-00) Free access to a selection of peer-reviewed biomedical research articles
- BioSupplyNet A catalog of biomedical suppliers (a catalog of catalogs)
- Cancer Genome Anatomy Project Gene expression, chromosomal alterations and polymorphisms associated with the cancer cell
- CancerNet Educational clinical material on the major cancers by the NCI
- Cooperative Breast Cancer Tissue Resource (CBCTR) A publicly funded supplier of primary breast cancer tissues with associated clinical and followup data
- Database of Expressed Sequence Tags (dbEST)
- Database Of Transcribed Sequences (DOTS)
- Ensembl Genome Browser
- Entrez An integrated search system for nucleotide sequences, protein sequences, biomedical literature (Medline), macromolecular structures, maps and genomes.
- ExPASy (Expert Protein Analysis System) A collection of proteomics tools, software and databases for protein sequence analysis and structure predictions
- GenBank Database providing an annotated collection of all publicly available DNA sequences
- Genome Browser (reviewed in Science 9-15-00) Excellent annotation tool for the human genome
- Genome Database A database of genomic mapping data
- Human Genic Bi-Allelic Sequences Database (reviewed in Science 5-5-00) Database of intragenic polymorphisms (SNPs)
- Human Protein Reference Database
- Human Transcript Database by the Baylor College of Medecine
- LocusLink A database of genetic loci for the human, mouse, rat, drosophila, and zebra fish genomes
- Medline Plus Health information (National Library of Medicine)
- Medscape (reviewed in Science 3-5-99) Various medical info
- Multiple Dictionary Search Engine More than 600 dictionaries including thesauri, acronyms, synonyms, grammar, multilingual translations, etc.
- National Cancer Institute US principal agency for cancer research
- National Center for Biotechnology Information (NCBI) Public databases for molecular biology
- National Human Genome Research Institute The NIH agency responsible for the human genome project
- National Library of Medicine (NLM) World's largest medical library (includes Medline)
- NIH Bioinformatics Web Site
- NIH Proteome Special Interest Group - Protein mass spectrometry and other protein analysis tools on the web.
- Online Mendelian Inheritance in Man (OMIM) A catalog of human genes and genetic disorders
- Protein Information Resource Includes the Protein Sequence Database and other valuable databases for searching protein information.
- Protocol Online (reviewed in Science 8-13-99) A catalog of laboratory protocols from diverse sources
- PubMed (Medline) Search tool for biomedical literature
- Signal Transduction Knowledge Environment (reviewed in Science 4-21-00) Includes maps of signaling networks and database of signal transduction molecules
- UniGene A catalog of human genes
- US Patent and Trademark Office search for issued patents.
- Web of Science Science Citation Index provided by the Institute for Scientific Information (ISI)
- The Whole Mouse Catalog (reviewed in Science 2-12-99) An extensive collection of links and resources for biomedical research using mice or rats
Dictionaries:
- American Heritage Dictionary of the English Language
- Britannica Online The complete Encyclopedia Britannica. Also contains an extensive and editor-reviewed internet guide.
- Life Science Dictionary (BioTech)
- Merriam-Webster OnLine Dictionary
- Multiple Dictionary Search Engine More than 600 dictionaries including thesauri, acronyms, synonyms, grammar, multilingual translations, etc.
- Online Medical Dictionary
Pharmaceutical Information
- AHFS drug information 2003 - Information on uses, dosages, routes and/or methods of administration beyond those included in FDA approved drug labeling
- Orange Book - Lists all FDA approved prescription drugs, including new and generic drugs. Updated monthly.
- Basic and clinical pharmacology, 2001 (online textbook)
- UTSW library resources - select electronic books. search by subject - pharmacology
- Pharmacopoeia
UTSW Specific:
- Campus Maps Location of each building in the UT Southwestern Medical Center
- Electronic Books from UT Southwestern Medical Center library
- NetLibrary A collection of electronic books to which UT Southwestern Medical Center library has subscribed - access from UTSW only
Cool Links:
- American Association for Cancer Research (AACR)
- American Universities A list of US university home pages. A more extensive list that include universities and colleges around the world may be found here
- Google A search engine in which the results are ranked according to the number of sites that link to them. The most "popular" sites are therefore listed first.
- Human Genome News Online newsletter on the genome projects (DOE)
- Human Genome Research The DOE's (Department of Energy) web site on the genome projects
- Human Genome Information The DOE Oak Ridge Educational Information resource, a really good place for basic genetics and genomics information.
- DNA Sequence Analysis Tools
- ELSI Ethical Legal and Social Issues on aspects of human genetics.
- Cancer & Genetics The site provides comprehensive links to reliable information about genes, their associated proteins, and genetic mutations associated with cancer and related disorders.
Genetic Testing, Counseling and Education:
- Genetics Testing Laboratory Directory A listing of US and international laboratories that test for a variety of diseases.
- GeneClinics Full-text articles on specific hereditary diseases.
Biotechnology Business:
