The Innovation Laboratory develops applied computational biology/bioinformatics applications, instrumentation and methods, especially focused to address important topics in genetics, genomics, biology and medicine. We have built devices and software solutions to facilitate rapid progress in biomedicine, and these have lead to a number of computational tools and databases that are available via the world wide web, a variety of instruments, some of which have been commercialized, some spin-off companies and a series discoveries in biology and medicine. The Innovation Laboratory staff is multi- disciplinary, including physicists, engineers, mathematicians, biologists and physicians. Another mission of the group is training, so members include graduate students, post-doctoral fellows, interns, faculty and numerous professional staff, and is always searching for talented and driven scientists. The Innovation Research and Development Laboratory personnel are engaged in a number of collaborations throughout the world, with academic and corporate institutions, supplying technology and conducting research in cancer, heart disease, drug discovery, biodefense, computer science and engineering.